Most Popular Cubensis Strains
An increasing amount of research is showing more or less conclusively that magic mushrooms, and psilocybin specifically, have measurable therapeutic and psychedelic mushroom effects depending upon mushroom strains.
As any amateur microscopist will tell you, there are countless different strains of magic mushroom species and strains with different effects and potency – that’s what makes them such a wonderful specimen for fungal taxonomy. There are also strain-specific therapeutic benefits, and what about the strongest cubensis strain or the most common psilocybin mushroom strains for magic mushroom enthusiasts?
- Different strains may have different benefits from a therapeutic standpoint
- Information on the cubensis mushroom strains topic is limited and how that could change in future psilocybin and magic mushroom research
- How limited anecdotal evidence has indicated that different strains do have different benefits

Why Different Magic Mushroom Strains May Have Different Therapeutic Applications
In most psilocybin research, such as clinical trials, the form of psilocybin being used has been synthesized. In other words, it’s pure psilocybin—like an extract. This makes accurate dosing much easier, and rules out the effects of any other compounds typically found in mushrooms, allowing for researchers to study the effects of psilocybin specifically.
In the field of psilocybin research, there’s a subsection of researchers who are proponents of what they call “whole fungi therapy.” The gist of the research is this: the benefit of psilocybin may be enhanced by the other compounds naturally found in the fungi, which explains the different effects people may experience when consuming different strains of mushroom.
Most Major Clinical Trials Haven’t Explored Cross-Strains or Strain-Specific Therapy
Major clinical trials and research have focused largely on the effects of psilocybin specifically, but a growing number of researchers are interested in learning more about the potential benefits of whole fungi therapy.
➢ Proprietary Hybrid Cross Strain of Psilocybe Cubensis Spores
If whole fungi therapy proves to be more beneficial than purified psilocybin doses, then it’s entirely possible we’ll see more and more research being done on whole fungi. Which naturally will lead to researchers investigating the different kinds of mushroom strains.
Anecdotal Evidence Indicates Different Strains May Be Effective for Different Purposes
Golden Teacher, Luminous Lucies, and Jedi Mind Fuck Strains
For now, most “research” into the different strains of psilocybin-containing mushrooms and their potential therapeutic effects are largely anecdotal. For example the Golden Teacher syringe spores are known to cause contemplative, introspective trips from their mushroom fruiting body. In nature however, the RIP Tide Mushroom is very potent.
Other magic mushroom strains, such as Luminous Lucies and the Jedi Mind Fuck have been reported by psychonauts as being a very visually-oriented experience.
While nobody can definitively say which psychedelic mushroom strain gives the “best trip”, our knowledge of cubensis mushrooms is growing each day as we hear customer feedback. At least anecdotally perhaps soon mainstream science will be following suit for taking advantage of physiological and psychological effects and potential benefits.